Hypnosis: a twilight zone of the top-down variety Few have never heard of hypnosis but most know little about the potential of this mind-body regulation technique for advancing science.

An early form of psychotherapy, hypnosis has been tarnished by a checkered history: stage shows, movies and cartoons that perpetuate specious myths; and individuals who unabashedly write 'hypnotist' on their business cards. Hypnosis is in the twilight zone alongside a few other mind-body exemplars. Although scientists are still unraveling how hypnosis works, little is mystical about this powerful top-down process, which is an important tool in the armamentarium of the cognitive scientist seeking to unlock topical conundrums.